Alkaloids from Narcissus serotinus

PIGNI, N. B.; ELAMRANI, A.; BENAISSA, M.; VILADOMAT, F.; CODINA, C.; BASTIDA, J.

Antalya

Conferencia; 6th CMAPSEEC 2010 (6th Conference on Medicinal and Aromatic Plants of Southeast European Countries); 2010

The Amaryllidaceae botanical family is well known for the presence of an exclusive group of alkaloids with a wide range of biological activities. Narcissus serotinus is a plant belonging to this family and its geographical distribution is mainly located along the Mediterranean coast. In the present work, specimens collected near Casablanca (Morocco) were used to study the alkaloid content of this specie. Starting with just 350 mg of the whole plant we used typical extraction and purification procedures to obtain fractions and compounds ready to analyze by GC/MS (Gas Chromatography/Mass Spectrometry) and NMR techniques. The preliminary results revealed the presence of lycorine and homolycorine type alkaloids. Some of the isolated compounds correspond to new alkaloids, one of wich has been previously published, but with an erroneous structure.